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N of 1 is a documentary series that highlights the promise of precision health to transform lives by harnessing diverse forms of health data and turning them into insights that lead to action — making healthcare more personal and precise.

N Of 1 episode intro video

The beginning screen of Verily’s N of 1 documentary series, highlighting the promise of precision health to transform lives.

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In this episode, the city of lights looks to a new innovation to help detect the presence of infectious disease: wastewater-based epidemiology. This innovation can measure pathogens in wastewater with almost real-time results, enabling quick action & prevention against the spread of diseases.

<h2>See how Vegas can outsmart the next pandemic</h2> Watch the full episode

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Beginning screen of video clip, showing an employee walking the Clark County Water Reclamation District — a government wastewater treatment agency.

<h3>Verily Sightline</h3>Solutions to monitor and mitigate population-level disease<a style='text-decoration:none; color:#d4e585' href='solutions/sightline'>Learn more</a>

Mother and son walking with zest in their community along the water on a drizzly day with a rainbow on the horizon.

A history of wastewater and the insight it can provide for our communities<a style='text-decoration:none; color: #c4cad1;' href='/perspectives/what-is-wastewater'>Read blog</a>

An infographic with an image of John Snow, a bacterium, and a wastewater treatment facility

A watershed moment at HLTH 2024<a style='text-decoration:none; color: #c4cad1;' href='/perspectives/watershed-moment-hlth-conference'>Read blog</a>

Enhancing Public Health Surveillance: Wastewater Monitoring banner

Verily Sightline: A New horizon in public health <a style='text-decoration:none; color: #c4cad1' href='/perspectives/sightline-public-health'>Read blog</a>

Of US population’s wastewater is captured by some of the largest facilities<a href='#superscript1' style='text-decoration:none'>1</a>

Clark County Water Reclamation District is a government wastewater treatment agency with over 100 acres of water treatment land

Employees having a discussion outside at the Clark County Water Reclamation District — a government wastewater treatment agency.

Close up of multiple wastewater pipes at Clark County Water Reclamation District.

Image of scientist in Verily lab being filmed for the N of 1 episode on wastewater epidemiology.

Neighborhoods in Clark County, Nevada, which includes the city of Las Vegas.

an employee working at the Clark County Water Reclamation District — a government wastewater treatment agency.

Collage of an employee of the Clark County Water Reclamation District — a government wastewater treatment agency.

“Las Vegas is a wonderful place for wastewater monitoring, because not only do we have 2.5 million residents here in the Las Vegas Valley — on any given day we have 300,000 tourists — and wastewater is another way to contribute to the health and welfare of this community. Our treatment facility processes over 115 million gallons of water daily, allowing us to see what’s going on in the Las Vegas Valley and the bustling Strip. We send our water samples to Verily and within 24 hrs get results about the levels of pathogens present in the wastewater. We can then share that information with our public health officials and they can take actions to keep our community safe. The local public health department has gained invaluable data that has aided in risk communication, intervention evaluation, resource allocation, and clinician education.”

“I'm part of a larger R&D group that looks at emerging challenges in the water industry. When we started doing wastewater monitoring, what was crazy to me was how accurate it was. It was spot on. It’s truly a portal into what’s happening in the community. With the results that we get from Verily, all the data is laid out, to be able to present it to our public health officials, so that they can understand what diseases might be out there, to keep that community safe and keep them healthy – without them having to do anything. It has proven to be an effective method for detecting the presence of various diseases circulating in a population, ranging from respiratory illnesses like SARS-CoV-2 and influenza to emerging threats such as mpox and hepatitis A.”

Collage of employees of the Clark County Water Reclamation District, and Dan Gerrity, Principal Research Scientist, Southern Nevada Water Authority.

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In this episode, we see how using AI to digitize clinical trial protocols can transform the way research sites conduct research. These new tools not only streamline research processes and bring treatments to market faster — they help to preserve our most precious resource — time.

<h2>Enabling human connections with AI for research</h2> Watch the full episode

N of 1 film excerpt: Doctor using stethoscope on participant.

<h3>Verily Digital Protocols</h3>AI-driven digital protocol solution<a style='text-decoration:none; color:#d4e585' href='/solutions/viewpoint#digital-protocols'>Learn more</a>

Collage of a PDF study protocols, clinical researcher and digitized protocol graph

The role of AI in powering digital protocols<a style='text-decoration:none;color: #c4cad1;' href='/perspectives/the-role-of-ai-in-powering-digital-protocols'>Read blog</a>

Role of AI in Powering Digital Protocols

Protocol digitization – What exactly is this transformative CTMS feature?<a style='text-decoration:none;color: #c4cad1;' href='/perspectives/protocol-digitization-what-exactly-is-this-transformative-ctms-feature'>Read blog</a>

Abstract visualization of geometric shapes

Solving burnout and tech overload in clinical research<a style='text-decoration:none;color: #c4cad1;' href='/perspectives/solving-burnout-and-tech-overload-in-clinical-research'>Read blog</a>

Clinical research professional standing at desk with hand on her head looking at paper

A traditional clinical trial startup time length — many can fail due to recruitment, design and data problems<a href='#superscript3' style='text-decoration:none'>3</a>

Increase of efficiency and speed of clinical trial start up time from digitization of protocols by the use of Viewpoint AI<a href='#superscript5' style='text-decoration:none'>*</a>

Doctor Andrew Trister, MD, PhD, and Verily’s Chief Medical and Scientific Officer.

A research manager, sorting through vast amounts of clinical trial protocol documents and files at the American Oncology Network, The Center for Cancer and Blood Disorders.

A research manager at the American Oncology Network, The Center for Cancer and Blood Disorders smiling during filming of Verily’s N of 1 docuseries.

An oncologist examining a patient

“When we get selected as a site, the sponsor will ship us out binders for everything. So we'll get this massive shipment of about 3 or 4 different binders. They have all of our protocols. Anybody who's touching any of our patients through the duration of our trial is going to be using this protocol, the pharmacy, for mixing all the medication, our nurses for infusing anything, any of the people, drawing all of our blood that all lives within this binder. So we cannot run our trial without this. Nobody can touch a patient without this. We're starting to digitize all of our protocols. We're using Verily CTMS – instead of having all these papers here, the protocol is going to be actually uploaded into the system. So we can just easily reference all the data we need within that system without having to come through these binders, through these folders and go page by page and look for things like that.”

Collage of a research team at the American Oncology Network, The Center for Cancer and Blood Disorders.

When I was referred to Dr. Boccia by my primary care physician. He came in with the results of a CAT scan that I'd had, and he did confirm that it was, in fact, multiple myeloma. You know when somebody hits you with that, it's, you just sort of freeze. It shakes you up a little bit when you get that cancer diagnosis. Like, what does this all mean? And I was told by people that I know, get into a clinical trial as soon as you can. Everything that Dr. Boccia has done for me has maintained my quality of life. I can walk to work, I can exercise, I can still play golf, and so I feel very fortunate about that.

Collage of a man participating in clinical research.

This episode explores how Verily is using AI to help clinicians and care teams prioritize higher risk patients and personalize care plans, from nutrition and exercise to the motivating prompts to keep people actively engaged in their health day to day.

<h2>See how AI helps care feel more human</h2> Watch the full episode

Video montage from the N of 1 episode showing Nini, a woman living with diabetes, managing her daily life with her son in East Harlem while using a health app to access diabetes care.

<h3>Verily Lightpath</h3>Intelligent chronic care solution<a style='text-decoration:none; color:#d4e585' href='/solutions/lightpath'>Learn more</a>

A woman with diabetes getting fitted with a CGM. She received the connected device for better diabetes management as part of her virtual care program.

Unlocking the potential of GLP-1 agonists<a style='text-decoration:none;color: #c4cad1;' href='/perspectives/unlocking-the-potential-of-glp-1-agonists'>Read blog</a>

Discover Dr. Sarah Thompson’s passion for innovating and humanizing chronic care<a style='text-decoration:none;color: #c4cad1;' href='/perspectives/discover-dr-sarah-thompsons-passion-for-innovating-chronic-care'>Read blog</a>

Image of Dr. Sarah Thompson, Verily Associate Chief Clinical Officer and Clinical Operations lead, speaking on a health conference panel.

Verily in ‘25 and beyond: powering AI for precision health<a style='text-decoration:none;color: #c4cad1;' href='/perspectives/verily-ai-precision-health-2025'>Read blog</a>

Abstract visualization of data platform showing a grid with lines representing threads of data.

Of U.S. adults had optimal cardiometabolic health in 2017-2018<a href='#superscript4' style='text-decoration:none'>4</a>

The proportion of U. S. adults with ideal body weight between 2000-2018, which fell from <a target='_blank' href='https://pubmed.ncbi.nlm.nih.gov/35798448/'>34%</a><a href='#superscript4' style='text-decoration:none'>4</a>

Dr. Carolyn Jasik being filmed in a stylish living room with mid-century modern design for the N of 1 episode.

Woman preparing a healthy salmon dish in her kitchen while filming the N of 1 episode.

Behind-the-scenes shot of Heike Sichtig, during the filming of N of 1, featuring the camera monitor and two crew members in the background.

Close up of Brooklyn bridge on a foggy day.

Close of of monitor feauturing Dr. Erich Huang during filming of N of 1 episode.

I think people with diabetes really need to know how what they eat affects their health. Having the app at my fingertips 24-7 was really helpful. It was great to have information in one place. I liked the fact that if there was a question that needed to be bumped up, I could be referred to someone like an actual doctor. You can do that on the go. It really just takes a few minutes. You don’t have to worry about booking a doctor's appointment or dropping into urgent care. Another feature of the app that I found particularly helpful was the meal logging agent. I can take a picture of my meal, and it lets me know information about the nutrition of what I was eating. I think that's really helpful to be able to do it right in the moment. It offers healthy meal options as alternatives to some of the not-so-healthy meals I’ve been eating — as well as healthy snacks and recipes.

Montage of scenes from filming the N of 1 episode, featuring a woman living with diabetes demonstrating healthy lifestyle choices.

I take Metformin, and I've been talking with my doctor. We've been considering one of the GLP-1s and she mentioned she thinks it'll be a really good aid for me to manage my levels.
For me, what appeals to me about taking a GLP-1 is that it's an injection and you only take it once a week. She said it could potentially replace the metformin, so I wouldn't have to be taking both. And that not only would it help manage my blood sugar, but it can also help with weight loss. You know, it's a no-brainer for me. It isn't a magic pill. It's definitely an aid. And you have to do the work to see results, managing what you're eating, having good nutritional habits, getting in enough water, and then walking or exercising — moving your body.

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Imagine healthcare as unique as you are, tailored precisely to your individual needs. “N of 1” is a documentary series that highlights the promise of precision health to transform lives by harnessing diverse forms of health data and turning them into insights that lead to action — making healthcare more personal and precise.

In research and statistics, “N of 1” refers to a study design where only one participant is involved. This means that the data is collected and analyzed from a single individual, rather than from a larger sample size.

N of 1 studies are often used in personalized medicine or case studies to investigate the effects of a specific intervention or treatment on an individual patient. They can provide valuable insights into the unique response of a patient to a particular therapy or condition.

Verily is an Alphabet health technology company focused on research, care, and public health to deliver on the promise of precision health and help people live healthier lives. We are uniquely positioned at the intersection of technology, data science, and healthcare to create tools to accelerate evidence generation, products to enable more personalized care, and approaches to manage disease at a population level.

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1American Society of Civil Engineers. A Comprehensive Assessment of America's Infrastructure: 2025 Report Card for America's Infrastructure. Published online.
<a href='https://infrastructurereportcard.org/cat-item/wastewater-infrastructure/' target='_blank'>https://infrastructurereportcard.org/cat-item/wastewater-infrastructure</a>2Lundeen, E., Burke-Conte, Z., Rein, D., et al. (2023, June 16). Prevalence of diabetic retinopathy in the US in 2021. JAMA Ophthalmology. Published online.
<a href='https://jamanetwork.com/journals/jamaophthalmology/fullarticle/2806093' target='_blank'>https://jamanetwork.com/journals/jamaophthalmology/fullarticle/2806093</a>3Shetty, A. (2024, March 5). Four steps to accelerate study start-up cycles. Applied Clinical Trials Online.<a href='https://www.appliedclinicaltrialsonline.com/view/four-steps-to-accelerate-study-start-up-cycles' target='_blank'>https://www.appliedclinicaltrialsonline.com/view/four-steps-to-accelerate-study-start-up-cycles</a>4O'Hearn, M., Lauren, B. N., Wong, J. B., Kim, D. D., & Mozaffarian, D. (2022). Trends and disparities in cardiometabolic health among U.S. adults, 1999–2018. Journal of the American College of Cardiology, 80(2), 138–151.<a target='_blank' href='https://www.jacc.org/doi/10.1016/j.jacc.2022.04.046'>https://www.jacc.org/doi/10.1016/j.jacc.2022.04.046</a> American Society of Civil Engineers. A Comprehensive Assessment of America's Infrastructure: 2025 Report Card for America's Infrastructure. Published online.
<a href='https://infrastructurereportcard.org/cat-item/wastewater-infrastructure' target='_blank'>https://infrastructurereportcard.org/cat-item/wastewater-infrastructure</a>*Compared to a baseline digitization process prior to the implementation of AI. Results seen at a Viewpoint Site CTMS client.

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